Alveolar Rhabdomyosarcoma Treatment; Depends On the Size, Location, and Stage of the Tumor

 

Alveolar Rhabdomyosarcoma Treatment

Alveolar Rhabdomyosarcoma Treatment often includes surgery, chemotherapy, and radiation therapy (radiotherapy). Moreover, the treatment of rhabdomyosarcoma has greatly improved the care of patients over the past few decades. Around 80% of patients with rhabdomyosarcoma (low-risk) can now be cured. Alveolar rhabdomyosarcoma (ARMS) refers to one subtype of the rhabdomyosarcoma family of soft tissue tumors. While, rhabdomyosarcoma is a rare type of cancer that forms in soft tissue; may occur at any age, often affects children.

Alveolar Rhabdomyosarcoma Treatment, such as chemotherapy, is given by injection into a vein. In North America, drugs such as cyclophosphamide (Neosar, Clafen, Cytoxan,), dactinomycin (Cosmegen, Lyovac Cosmegen), and vincristine (Vincasar, Oncovin) are commonly used to treat rhabdomyosarcoma. This combination of drugs is often called Vincristine, actinomycin D, and cyclophosphamide (VAC), an abbreviation for a chemotherapy combination used to treat rhabdomyosarcoma in children.

According to American Cancer Society, around 400 to 500 new cases of rhabdomyosarcoma (RMS) occur each year in the United States. Rhabdomyosarcoma is slightly more common in boys than in girls. Around 70% of people with rhabdomyosarcoma survive five years or longer. However, it depends on several factors, such as age, location, and size of the original tumor. Thus, there is an increasing demand for alveolar rhabdomyosarcoma treatment in this region. Alveolar rhabdomyosarcoma most often occurs on the chest, legs, arms, and stomach.

However, the exact cause of ARMS is unknown, and is associated with other conditions, such as Costello syndrome, Cardio-facio-cutaneous syndrome, Li-Fraumeni syndrome, Beckwith-Wiedemann syndrome, and Neurofibromatosis type 1. It can be diagnosed with the help of a biopsy, positron emission tomography (PET) scan, bone scan, magnetic resonance imaging (MRI), computed tomography (CT) scan, and X-ray imaging, in order to plan suitable alveolar rhabdomyosarcoma treatment.

Radiotherapy and chemotherapy are widely used to reduce the size of tumors before surgery, as well as to reduce the risk of cancer recurrence after surgery.

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