Bone Graft Substitutes Are Becoming Popular Choice Of Surgeons As They Are Available In Several Different Types Catering Patients’ Requirements
Bone Graft Substitutes |
Bone
grafts have been used for years to fill in missing bones in the body. The
process was first developed in the 19th century, however, is now a widely used
surgery. About 10% of all orthopaedic and trauma surgeries result in a bone
defect. Today, there are several different types of bone grafts available to
surgeons. Some of these are more expensive than others, still the long-term
results of these surgeries are well worth it. There are several types of bone
graft substitutes available on the market. Traditional autologous bone grafting
is one of the most commonly used options, and alternative bone grafting comes
from the iliac crest or other local sources. There are six main categories of
alternative bone implantation: nonstructural allograft, cadaver allograft,
demineralized bone granules, synthetic bone granules, and autologous cellular
gratings. Each of these products has a different regulatory pathway, and the
data required to be published vary.
Currently,
DBM is the most common choice among Bone
Graft Substitutes. It is biodegradable and has both
osteoinductive and osteogenic actions. It comes in different forms such as
injectable paste, graft, gel, crunch, and flex. Some are embedded with collagen
type I or osteoconduction and others are a combination of both. However, the
most important characteristic of an ideal bone substitute is that it should be
resorbable.
The most
ideal type of bone graft substitute is thermo-conductive, sterilizable, and
readily available. However, not every type of bone graft substitute is approved
for use in surgery. A surgeon must choose a bone graft substitute based on
specific criteria. Listed below are some examples of popular bone graft
substitutes. Several types of bone substitutes are available commercially.
The most suitable option is one that is biocompatible, biodegradable, and easy
to use and as long as it's biocompatible, it will be an excellent choice for
orthopedic surgery. So, there are many other alternatives for bone grafts. All
of them have some important advantages. In February 2022, the Food and Drug
Administration granted breakthrough device designation to Biomaterials Ltd.’s
Bonalive, which is a bone graft substitute that can potentially protect against
microbial colonization.
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