Mesenchymal stem cells (MSC) is one of the great breakthroughs in medical research and treatment of various disease
Mesenchymal stem cells |
The
mesoderm is a tissue rich in cellular DNA, which plays a key role in the
regeneration and maintenance of the human body. Mesenchymal stem cells (stem
cells obtained from the mesoderm) are actually adult stem cells that can
separate into various different cell types, including differentiated
cell-surface (Duceril's layer) and differentiated cell-hypoderm (DIH). Dancer,
a cancer patient who had used these cells to treat his cancer in the past, it
was discovered that his cancer had begun his successful treatment using these
cells.
Since
adult stem cells were first discovered around 20 years ago, they have been a
major research subject. Adult stem cells are now being used by scientists in
the areas of tissue engineering and regenerative medicine, to replace body
tissue that has been damaged, after it has been injured. One application that
these stem cells have been successfully tested for is in treating Crohn's
Disease in patients that are dealing with this disease as their age advances.
Moreover, applying Mesenchymal
Stem Cells directly to the site of the inflammation can relieve
the pain that the patient is facing.
Mesenchymal
stem cells are primarily found in the bone marrow in the form of circulating
stellate cells. These cells secrete an abundance of proteins (osteoproteins)
which aid in the maintenance of the bone marrow. The most abundant protein
found in Mesenchymal Stem Cells is the Sox; this protein is necessary in order
for the Dancer's cancer cells to survive. Other important proteins produced by
Mesenchymal Stem Cells include fibrin and a-tubulin, which help maintain the
structure of the skeletal system.
Scientists
have been investigating for years how MSCs may be utilized to treat various
bone and cartilage illnesses. Some MSC research is investigating treatments for
cancer. Scientists have found that MSCs are responsible for a lot of aspects of
health in both humans and animals. For example, they form a protective layer
along the exterior of bones where other tissues settle. In addition to that
role, the mesenchymal cell types also promote the growth of new cartilage,
synovial fluid, and other cells in the body. In the bone marrow, the MSCs may
also play a role in producing antibodies that aid in the body's fight against
many infections. It is believed by some researchers that the use of MSCs
reduces the risk of the disease and improves the quality of life.
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Another
important use of the MSCs called a primary culture of bone marrow in vitro has
been made possible by using mscs cells called myoepidermal-derived cells. These
cells are produced from myoepidermal tissue that has not been differentiated
and grown in the laboratory. By using these cells, scientists have been able to
culture different types of tissues and also differentiate them.
Mesenchymal
stem cells also have some beneficial effects on various diseases in both
animals and humans. In animals like dogs, it has been observed that the
myoepidermal cells to help treat bone marrow disease in a much faster and
efficient manner. This is due to the fact that the myoepidermal cells are able
to prevent the accumulation of amorphous calcium salts in the bone marrow. This
prevents the disease from progressing.
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