The High Prevalence Of HIV Infection Worldwide Is Anticipated To Open Up New Avenues For The Integrase Inhibitors Market
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| Integrase Inhibitors Market |
The integrase inhibitors market is estimated to be valued at US$ 29.34 Bn in 2023 and is expected to exhibit a CAGR of 3.9% over the forecast period 2023-2030, as highlighted in a new report published by Coherent Market Insights.
Market Overview:
Integrase inhibitors are used to treat HIV infection by blocking the integrase
enzyme and preventing viral DNA from integrating into the genetic material of
human cells. Some key integrase inhibitors products include Isentress,
Biktarvy, Genvoya and others. These drugs have shown high efficacy in
suppressing HIV and are widely adopted as first-line treatment options.
The integrase inhibitors market is driven by the rising prevalence of HIV/AIDS
worldwide and growing adoption of generic integrase inhibitors. According to
UNAIDS, around 38 million people were living with HIV globally in 2020.
Furthermore, integrase inhibitors have demonstrated superior antiviral potency
and higher barrier to resistance compared to other drug classes, accounting for
their increasing preference over other antiretroviral medications. However, the
market faces challenges from stringent regulatory processes for new drug
approvals and high R&D costs associated with drug development.
Segment
Analysis
The integrase inhibitors market is segmented into integrase strand transfer
inhibitors (INSTIs) and allosteric integrase inhibitors. Among these, the
INSTIs segment dominated the market and accounted for the largest share of more
than 95% in 2021. This is primarily because INSTIs are preferred over other ARV
drug classes for their higher efficacy, lower toxicity levels, and high genetic
barrier to resistance. Some of the leading INSTI drugs include Bictegravir,
Cabotegravir, and Dolutegravir, which are widely adopted by patients and
healthcare providers due to their clinical effectiveness.
PEST Analysis
Political: Government initiatives to spread awareness about HIV treatment and
support research on innovative drugs are boosting market growth. However,
pricing pressures and stringent regulatory norms can hamper revenue generation.
Economic: Growing healthcare expenditures, rising disposable incomes, and
increasing funding for HIV treatment programs in developing nations are fueling
market expansion.
Social: Technological advancements in medicine and increasing acceptance of HIV
treatments are positively impacting the market. However, social stigma persists
which deters patients from seeking proper care.
Technological: Novel drug delivery modes such as long-acting injections of
INSTIs are being developed to improve treatment adherence and quality of life
for patients.
Key Takeaways
Global
Integrase Inhibitors Market Size is expected to witness high growth,
exhibiting a CAGR of 3.9% over the
forecast period due to increasing prevalence of HIV infections. The market was
sized at US$ 29.34 Bn in 2023.
On the regional front, North America dominated and accounted for over 35% of
the global market share in 2023 driven by high treatment uptake, presence of
leading vendors, and availability of advanced healthcare facilities. However,
Asia Pacific is anticipated to register fastest growth during the forecast
period supported by rising HIV burden, improving access to diagnosis &
treatment, and growing focus of international organizations.
Key players operating in the Integrase Inhibitors market are Gilead Sciences,
ViiV Healthcare, Merck & Co., Inc., GlaxoSmithKline PLC, Bristol-Myers
Squibb Company, Johnson & Johnson, AbbVie Inc., Janssen Pharmaceuticals,
Inc., Theratechnologies Inc., and Shionogi & Co., Ltd. Major players are
focusing on developing long-acting formulations to strengthen their market
position.
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